In adults with migraine and previous preventive treatment failures, a single infusion of a monoclonal antibody to pituitary adenylate cyclase–activating polypeptide led to fewer migraine days per month than placebo over the next 4 weeks.
The New England Journal of Medicine: Search Results in Endocrinology
In June 2019, a man presented with fever and severe illness in Inner Mongolia. An orthonairovirus was identified as a potential cause. This agent was identified in an additional 16 patients and was found in ticks.
The New England Journal of Medicine: Search Results in Infectious Disease
A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission.
The New England Journal of Medicine: Search Results in Allergy/Immunology
One hundred years ago, a 24-year-old man was admitted to the hospital because of fever, cough, and shortness of breath. The patient died on the fourth hospital day. A diagnosis was made.
The New England Journal of Medicine: Search Results in Pulmonary/Critical Care
In four patients with severe autoimmune disease, teclistimab, a bispecific antibody to B-cell maturation antigen and CD3, resulted in autoantibody reduction and clinical response after short-term follow-up.
The New England Journal of Medicine: Search Results in Allergy/Immunology
Preventive treatment for migraine is indicated when treatment of individual headache attacks is not sufficiently reliable or helpful, when such treatment must be taken so often that it is impractical or has adverse consequences, or when attacks cause profound disability. Approximately a third of adults who seek treatment for migraine…
The New England Journal of Medicine: Search Results in Endocrinology
In this trial involving patients with acute ischemic stroke treated with thrombolysis within 3 hours after symptom onset, the use of adjunctive intravenous argatroban or eptifibatide did not improve 90-day poststroke outcomes.
The New England Journal of Medicine: Search Results in Pulmonary/Critical Care
A 9-year-old girl presented with a 7-day history of a lesion on the left cheek and a 4-day history of fever. Treatment for possible impetigo had not alleviated the symptoms.
The New England Journal of Medicine: Search Results in Dermatology
In four patients with severe autoimmune disease, teclistimab, a bispecific antibody to B-cell maturation antigen and CD3, resulted in autoantibody reduction and clinical response after short-term follow-up.
The New England Journal of Medicine: Search Results in Dermatology
Preventive treatment for migraine is indicated when treatment of individual headache attacks is not sufficiently reliable or helpful, when such treatment must be taken so often that it is impractical or has adverse consequences, or when attacks cause profound disability. Approximately a third of adults who seek treatment for migraine…
The New England Journal of Medicine: Search Results in Neurology/Neurosurgery
