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A woman with refractory thrombocytopenia complicating systemic lupus erythematosus had a response to CD19 CAR T cells with an increase…

The addition of blinatumomab to consolidation chemotherapy in adults with B-cell precursor acute lymphoblastic leukemia who had minimal residual disease–negative…

A preterm baby boy was noted to have hepatomegaly on the first day of life. Radiographs of the baby’s legs…

Sotorasib led to clinical improvement in two patients with disabling vascular malformations driven by the KRAS mutation G12C. ​   The New…

Metabolic dysfunction–associated steatohepatitis (MASH) is the most common liver disease worldwide, and its prevalence is increasing rapidly.1 Yet, effective treatments…

Untreated HIV infection increases the risk of tuberculosis. Diagnosis and treatment are challenging, and access to preventive therapy is limited.…

In this randomized, controlled trial involving women in South Africa and Uganda, twice-yearly subcutaneous lenacapavir was superior to daily oral…

Preexposure prophylaxis is emerging as an important tool to prevent HIV-1 infection. This report describes an altered presentation of acute…

Given the 40 years of research and the wealth of successful tools that have been developed to prevent, diagnose, treat,…

New England Journal of Medicine, Ahead of Print. ​   massmed: New England Journal of Medicine: Table of Contents