Influenza A(H5N1) viruses are an emerging zoonotic threat and have spread widely throughout birds in North America. Recently, influenza A(H5N1) infection led to serious illness in a teenager in Canada.

​   The New England Journal of Medicine: Search Results in Infectious Disease

From March through October 2024, a total of 46 human cases of highly pathogenic avian influenza A(H5N1) virus infections were identified in the United States, with 20 linked to poultry exposure and 25 to dairy cow exposure.

​   The New England Journal of Medicine: Search Results in Infectious Disease

Highly pathogenic avian influenza (HPAI) A(H5N1) emerged in 1997.1 Since then, it has spread globally by migratory birds, resulting in infections in animals on every continent. HPAI A(H5N1) clade 2.3.4.4b emerged in 2021 and resulted in fatal infections in poultry as well as terrestrial and marine mammals.1

​   The New England Journal of Medicine: Search Results in Infectious Disease

A 63-year-old man with a history of CABG presented with a 2-month history of angina during exertion of the left arm. Angiography revealed retrograde flow in the left internal thoracic artery graft (shown in a video).

​   The New England Journal of Medicine: Search Results in Cardiology

New England Journal of Medicine, Ahead of Print.

​   massmed: New England Journal of Medicine: Table of Contents

New England Journal of Medicine, Ahead of Print.

​   massmed: New England Journal of Medicine: Table of Contents

New England Journal of Medicine, Ahead of Print.

​   massmed: New England Journal of Medicine: Table of Contents

New England Journal of Medicine, Ahead of Print.

​   massmed: New England Journal of Medicine: Table of Contents

To achieve goals focused on diversity in clinical research, trials may need to enroll large numbers of U.S. participants. But diversity initiatives and multiregional strategies can be complementary.

​   The New England Journal of Medicine: Search Results in Infectious Disease