Targeting CSF1R in Chronic GVHD — Lessons in Translation

Chronic graft-versus-host disease (GVHD) remains a rare and unacceptably debilitating autoimmune-like syndrome that afflicts patients in whom a blood disorder or cancer is otherwise cured by means of allogeneic hematopoietic stem-cell transplantation (HSCT). After allogeneic HSCT is performed, ongoing loss of T-cell and B-cell immune tolerance occurs as a new…

​   The New England Journal of Medicine: Search Results in Hematology/Oncology