Protection against Alzheimer’s Disease with APOE Christchurch Variant — How?

Protective variants of genetic loci are of particular interest for two reasons: first, because they are important from a clinical genetic perspective; and second, because they may give mechanistic clues about potential therapeutic strategies. In Alzheimer’s disease, the most prevalent protective allele is APOE2 (encoding apolipoprotein E2), which…

​   The New England Journal of Medicine: Search Results in Neurology/Neurosurgery