Epigenetic Therapy in a Rare Ovarian Cancer — A Double-Edged Sword
A woman with a rare ovarian tumor driven by EZH2 activity responded to tazemetostat, an EZH2 inhibitor, but T-cell acute lymphoblastic leukemia later developed.
The...
Acute Epiploic Appendagitis
A woman presented with dull, intermittent lower abdominal pain on the left side. CT of the abdomen showed an ovoid lesion adjacent to the...
Belzutifan versus Everolimus for Advanced Renal-Cell Carcinoma
In participants with advanced renal-cell carcinoma, belzutifan, a HIF-2α inhibitor, was superior to everolimus, an mTOR inhibitor, with respect to progression-free survival and tumor...
Why Was the Azithromycin “for Life” Trial Necessary?
In 2009, a cluster-randomized trial showed a 49% reduction in all-cause mortality among Ethiopian children 1 to 9 years of age in the year...
Why Was the Azithromycin “for Life” Trial Necessary?
In 2009, a cluster-randomized trial showed a 49% reduction in all-cause mortality among Ethiopian children 1 to 9 years of age in the year...
