A New Orthonairovirus Associated with Human Febrile Illness
In June 2019, a man presented with fever and severe illness in Inner Mongolia. An orthonairovirus was identified as a potential cause. This agent...
A Monoclonal Antibody to PACAP for Migraine Prevention
In adults with migraine and previous preventive treatment failures, a single infusion of a monoclonal antibody to pituitary adenylate cyclase–activating polypeptide led to fewer...
Teclistamab-Induced Remission in Refractory Systemic Lupus Erythematosus
A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3)...
BCMA-Targeted T-Cell–Engager Therapy for Autoimmune Disease
In four patients with severe autoimmune disease, teclistimab, a bispecific antibody to B-cell maturation antigen and CD3, resulted in autoantibody reduction and clinical response...
Case 27-2024: A 24-Year-Old Man with Pain and Dyspnea
One hundred years ago, a 24-year-old man was admitted to the hospital because of fever, cough, and shortness of breath. The patient died on...
