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Alternative Complement Pathway Inhibition with Iptacopan in IgA Nephropathy

Among patients with IgA nephropathy, treatment with iptacopan, which inhibits the alternative complement pathway, resulted in a significant reduction in proteinuria as compared with...

A Milestone for Gene-Editing Therapies

New England Journal of Medicine, Ahead of Print. ​   massmed: New England Journal of Medicine: Table of Contents

Microvascular Inflammation of Kidney Allografts and Clinical Outcomes

New England Journal of Medicine, Ahead of Print. ​   massmed: New England Journal of Medicine: Table of Contents

CRISPR-Based Therapy for Hereditary Angioedema

New England Journal of Medicine, Ahead of Print. ​   massmed: New England Journal of Medicine: Table of Contents

CRISPR-Based Therapy for Hereditary Angioedema

In this randomized, controlled trial, the number of angioedema attacks per month was approximately 75% lower among adults with hereditary angioedema who received a...

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