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Left Atrial Appendage Closure after Ablation for Atrial Fibrillation

After atrial fibrillation ablation, left atrial appendage closure was associated with a lower risk of bleeding than oral anticoagulation and was noninferior to oral...

CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy

A phase 1 trial of nexiguran ziclumeran (nex-z) to treat transthyretin cardiomyopathy showed a rapid and durable reduction of 90% in serum transthyretin levels...

NEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy

In this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research being presented at the 2024 American Heart Association Scientific Sessions....

Intensive Blood-Pressure Control in Patients with Type 2 Diabetes

In this trial, patients with type 2 diabetes had a lower incidence of major cardiovascular outcomes with a systolic blood-pressure target of less than...

NEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity

In this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research being presented at the 2024 American Heart Association Scientific Sessions....

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