Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer
The combination of nivolumab and ipilimumab in patients with metastatic colorectal cancer led to 24-month progression-free survival of 72%, as compared with 14% with...
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
Among patients with triple-negative breast cancer, 5-year survival was 86.6% with neoadjuvant pembrolizumab with chemotherapy followed by adjuvant pembrolizumab and 81.7% with neoadjuvant chemotherapy...
NEJM at ESMO — Overall Survival with Pembrolizumab in Early-Stage Triple- Negative Breast Cancer
In this audio interview, Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research being presented at the 2024 European Society of...
Degenerative Rotator-Cuff Disorders
Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some...
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam
In this cluster-randomized trial in Vietnam, a two-dose PCV10 vaccination schedule was not inferior to the routine three-dose schedule in preventing vaccine serotype carriage...
