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Reducing the Cost of Saving Children’s Lives

The use of pneumococcal conjugate vaccines has been associated with a major reduction in mortality and morbidity from pneumococcal disease among young children worldwide,...

Fractional Doses of Pneumococcal Conjugate Vaccine — A Noninferiority Trial

Pneumococcal conjugate vaccines are an important but costly part of childhood vaccination. This trial assessed immunogenicity of fractional-dose regimens — a key consideration as...

A Case of Vertical Transmission of Oropouche Virus in Brazil

In a woman who had Oropouche virus infection in the third trimester of pregnancy followed by stillbirth, phylogenomic results confirmed the link between this...

Case 37-2024: A 41-Year-Old Man with Seizures and Agitation

A 41-year-old man with epilepsy presented with increased seizure activity. In the hospital, the patient struck a staff member and said, “I thought they...

Immunotherapy for Early-Stage Triple-Negative Breast Cancer

Early-stage triple-negative breast cancers, which lack expression of three proteins (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2), have long been...

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