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Case 16-2024: A 20-Year-Old Man with a Pustular Rash

A 20-year-old man was evaluated for a pustular rash that had progressed over a period of several days. The lesions were at various stages...

Video versus Direct Laryngoscopy for Urgent Intubation of Newborn Infants

Intubation in neonates is challenging, and repeated attempts are associated with adverse events. Among neonates undergoing urgent intubation, video laryngoscopy resulted in more successful...

Exceptional Genetics, Generalizable Therapeutics, and Coronary Artery Disease

The increasingly widespread availability of genomic sequencing has enabled the identification of persons and families with uniquely favorable traits, including a very low incidence...

Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia

This phase 2b trial of a short interfering RNA that targets ANGPTL3 showed substantive dose-dependent lowering of triglyceride levels. ​   The New England Journal of Medicine:...

Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia

New England Journal of Medicine, Ahead of Print. ​   massmed: New England Journal of Medicine: Table of Contents

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