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Global Health Law for a Safer and Fairer World

After Covid-19, the global health community must address major gaps in global preparedness, critical capacities needed for a safer and fairer world, and international...

Sixty Years of Hemodynamic Pharmacology in Obstructive Hypertrophic Cardiomyopathy

In April 1964, leading cardiologists, cardiovascular surgeons, and pathologists convened in London for a 2-day symposium to discuss a relatively new disease entity that...

Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy

Among patients with symptomatic obstructive hypertrophic cardiomyopathy, treatment with aficamten led to a greater increase in peak oxygen consumption than placebo at 6 months. ​   The...

Efficacy and Safety of Donidalorsen for Hereditary Angioedema

A randomized, controlled trial of donidalorsen, which targets prekallikrein mRNA, in patients with hereditary angioedema showed a lower attack rate in the treatment groups...

Adding Insult to Injury

This interactive feature describes a 44-year-old woman with sickle cell disease who presented to the emergency department with pain throughout her body. She was...

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