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Congenital Syphilis

A preterm baby boy was noted to have hepatomegaly on the first day of life. Radiographs of the baby’s legs showed periostitis and alternating...

Brief Report: Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation

Sotorasib led to clinical improvement in two patients with disabling vascular malformations driven by the KRAS mutation G12C. ​   The New England Journal of Medicine: Search...

Dual Agonists for Management of Metabolic Dysfunction–Associated Steatohepatitis

Metabolic dysfunction–associated steatohepatitis (MASH) is the most common liver disease worldwide, and its prevalence is increasing rapidly.1 Yet, effective treatments for MASH remain scarce....

HIV-Associated Tuberculosis

Untreated HIV infection increases the risk of tuberculosis. Diagnosis and treatment are challenging, and access to preventive therapy is limited. This review addresses recent...

Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women

In this randomized, controlled trial involving women in South Africa and Uganda, twice-yearly subcutaneous lenacapavir was superior to daily oral emtricitabine–tenofovir disoproxil fumarate in...

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