Brief Report: Neutralizing Autoantibodies against Interleukin-10 in Inflammatory Bowel Disease
Two children with inflammatory bowel disease had neutralizing anti–interleukin-10 autoantibodies. One child had durable drug-free remission after B-cell depletion and an associated decrease in...
Parkinson’s Disease
Parkinson’s disease is a multisystem neurodegenerative disorder with motor and prominent, sometimes premonitory, nonmotor symptoms. Detection of gene variants may inform prognosis and, potentially,...
Intention to Treat: Race-Based Diagnosis, Part 3 — ITT Episode 35
As race-based diagnostic tools, such as pulse oximeters that function poorly on darker skin, continue to lead to inequitable care, a growing movement is...
Science behind the Study: Kidney Disease and Antinephrin Antibodies
This editorial describes the science behind detecting and treating autoimmunity in kidney disease.
The New England Journal of Medicine: Search Results in Pediatrics
Going Down the Rabbit Hole
A previously healthy 8-year-old girl was transferred to a Boston hospital from Nantucket (an island off the coast of Massachusetts) with a 12-day history...
