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Science behind the Study: Inhibiting IgG in Hemolytic Disease of the Fetus

This editorial describes the science behind a study of the monoclonal antibody nipocalimab to postpone or prevent intrauterine transfusion in pregnancies at high risk...

Postacute Sequelae of SARS-CoV-2 Infection in the Pre-Delta, Delta, and Omicron Eras

SARS-CoV-2 infection leads to postacute sequelae in many organ systems. In this study, the risk of postacute sequelae decreased over time but remained substantial...

En Coup de Sabre

A 70-year-old woman presented with a 1-year history of progressive indentation and darkening of the skin of her forehead. On examination, there was a...

Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn

In a trial involving 13 pregnancies at high risk for early-onset severe hemolytic disease of the fetus and newborn, nipocalimab increased the percentage with...

Myeloma Therapy for Monoclonal Gammopathy of Thrombotic Significance

A patient with serious thrombotic episodes was found to have a monoclonal gammopathy of an anti–PF4 antibody. Myeloma therapy reduced the paraprotein level and...

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