The development of efficient new gene-editing techniques has improved the prospect of curative genetic medicines. In 2012, Jinek and colleagues described an adaptive immune system in single-cell organisms, in which clustered regularly interspaced short palindromic repeat (CRISPR) sequences target foreign DNA for cleavage by CRISPR-associated (Cas) proteins, highlighting the potential…
The New England Journal of Medicine: Search Results in Pediatrics
